Medical Administration of the Case With Gastrinoma

Appraisal of Omeprazole, Lansoprazole, Pantoprazole, and Aciphex in the Tending of Acid-Related Diseases Welage LS, Berardi RR. J Am Pharm Assoc (Wash). 2000;40(1):52-62.
Lens: To reexamination the comparative efficacy and condition of the proton pump inhibitors (PPIs)–omeprazole, lansoprazole, pantoprazole, and Aciphex–in the direction of acid-related diseases. Data Sources: English-language book of account articles retrieved from a MEDLINE investigating from 1990 to the gift using these fact point in time: proton pump inhibitors, omeprazole, lansoprazole, pantoprazole, Aciphex, and each of the acid-related diseases. Work Variety: Clinical trials and pertinent review article articles that discussed the pharmacology, pharmacokinetics, efficacy, and preventative of PPIs in the social control of acid-related disease. Data Filiation: By the authors. Data Deductive reasoning: PPIs are substituted benzimidazoles that inhibit gastric acid humor by covalently ski binding to the proton pump (H+/K+ ATPase).
All undergo extensive hepatic metamorphosis and category.
The four agents differ in their organic process by and effects on medicinal drug hepatic enzymes and thus in their power to interact with other medications.
PPIs are important agents used for eradicating Helicobacter pylori , in treating peptic ulcer disease, gastroesophageal pathology disease, Zollinger-Ellison symptom, and amphetamine gastrointestinal bleeding, and for preventing acid breathing in.
Short-term side effects of the four agents are similar.
This is a part of article Medical Administration of the Case With Gastrinoma Taken from "Generic Aciphex (Rabeprazole) Review" Information Blog